[et_pb_section fb_built=”1″ _builder_version=”4.24.2″ _module_preset=”default” positioning=”none” z_index=”2″ custom_margin=”|20px||20px|false|true” custom_margin_tablet=”|20px||20px|false|true” custom_margin_phone=”|10px||10px|false|true” custom_margin_last_edited=”on|phone” custom_padding=”||62px|||” border_radii=”on|20px|20px|20px|20px” border_radii_tablet=”on|20px|20px|20px|20px” border_radii_phone=”on|15px|15px|15px|15px” border_radii_last_edited=”on|phone” locked=”off” global_colors_info=”{}”][et_pb_row column_structure=”1_3,1_3,1_3″ module_id=”section1″ _builder_version=”4.14.2″ _module_preset=”default” width=”100%” width_tablet=”” width_phone=”90%” width_last_edited=”on|phone” custom_margin=”5px|auto||auto||” custom_padding=”8px|||||” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”4.24.2″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/odalerts.cste.org\/wp-content\/uploads\/2026\/03\/respondbreadcrumb.png” title_text=”respondbreadcrumb” _builder_version=”4.14.2″ _module_preset=”default” width=”64%” custom_margin=”-27px||||false|false” filter_opacity=”80%” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.24.2″ _module_preset=”default” global_colors_info=”{}”][dipi_dual_heading first_heading=”Generate Possible” second_heading=”Explanations” heading_tag=”h1″ heading_display=”column” fh_padding=”0px|20px|20px|20px|false|true” sh_style=”background” sh_background_style=”normal” sh_padding=”0px|20px|20px|20px|false|true” sh_margin=”-30px|0px|0px|20px|false|false” fh_padding_tablet=”0px|20px|20px|20px|false|true” fh_padding_phone=”0px|20px|20px|20px|false|true” fh_padding_last_edited=”on|desktop” fh_margin_last_edited=”off|desktop” sh_padding_tablet=”0px|20px|20px|20px|false|true” sh_padding_phone=”0px|20px|20px|20px|false|true” sh_padding_last_edited=”on|desktop” 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back_side_bg_color_gradient_type=”linear”][\/dipi_dual_heading][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.14.2″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.24.2″ _module_preset=”default” width_tablet=”” width_phone=”90%” width_last_edited=”on|phone” custom_margin=”-51px|auto|14px|auto||” custom_padding=”||0px||false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.24.2″ _module_preset=”default” global_colors_info=”{}”][et_pb_blurb image_icon_width=”40px” icon_alignment=”left” content_max_width=”100%” _builder_version=”4.14.2″ _module_preset=”default” header_text_color=”#071018″ header_font_size=”22px” header_letter_spacing=”-0.2px” header_line_height=”1.2em” body_font=”Poppins||||||||” body_text_color=”#64748B” body_font_size=”20px” body_line_height=”1.4em” text_orientation=”center” custom_margin=”15px||80px|0px|false|false” custom_padding=”|56px||56px|false|true” 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[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row use_custom_gutter=”on” gutter_width=”2″ make_equal=”on” custom_padding_last_edited=”on|phone” _builder_version=”4.14.2″ _module_preset=”default” background_color=”#071018″ width=”68%” width_tablet=”” width_phone=”90%” width_last_edited=”on|phone” custom_padding=”20px|45px|47px|45px|false|true” custom_padding_tablet=”20px|20px|20px|20px|true|true” custom_padding_phone=”10px|10px|10px|10px|true|true” border_radii=”on|15px|15px|15px|15px” border_width_all=”1px” border_color_all=”rgba(100,116,139,0.5)” border_width_bottom=”0px” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.24.2″ _module_preset=”default” global_colors_info=”{}”][et_pb_accordion open_toggle_text_color=”#7ED3FC” open_toggle_background_color=”RGBA(255,255,255,0)” closed_toggle_background_color=”RGBA(255,255,255,0)” icon_color=”#FFFFFF” _builder_version=”4.14.2″ _module_preset=”default” toggle_font=”Poppins||||||||” toggle_text_align=”left” toggle_font_size=”19px” body_font=”Poppins|300|||||||” body_text_align=”center” body_text_color=”#FFFFFF” body_font_size=”16px” border_radii=”off|20px|20px||” border_width_all=”0px” global_colors_info=”{}”][et_pb_accordion_item title=”1. Review Existing Records” open=”on” open_toggle_text_color=”#FFFFFF” closed_toggle_text_color=”#FFFFFF” _builder_version=”4.14.2″ _module_preset=”default” border_width_bottom=”0.8px” border_color_bottom=”#64748B” global_colors_info=”{}” toggle_text_color=”#FFFFFF”]<\/p>\n
Start with a thorough review of available records:<\/p>\n
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These records can reveal clusters, common symptoms, locations, or substances involved, providing early signals of a pattern.<\/p>\n
[\/et_pb_accordion_item][et_pb_accordion_item title=”2. Conduct Case Interviews” open_toggle_text_color=”#FFFFFF” closed_toggle_text_color=”#FFFFFF” _builder_version=”4.14.2″ _module_preset=”default” border_width_bottom=”0.8px” border_color_bottom=”#64748B” global_colors_info=”{}” toggle_text_color=”#FFFFFF” open=”off”]<\/p>\n
Interview individuals who:<\/p>\n
Ask about:<\/p>\n
Tip:<\/strong> Use trauma-informed interviewing practices and ensure participant confidentiality. Community-based organizations that serve people who use drugs may be helpful in facilitating trust and access.<\/span><\/p>\n [\/et_pb_accordion_item][et_pb_accordion_item title=”3. Consider Laboratory Testing” open_toggle_text_color=”#FFFFFF” closed_toggle_text_color=”#FFFFFF” _builder_version=”4.14.2″ _module_preset=”default” border_width_bottom=”0.8px” border_color_bottom=”#64748B” global_colors_info=”{}” toggle_text_color=”#FFFFFF” open=”off”]<\/p>\n Laboratory testing helps detect emerging drug threats and inform outbreak\u00a0response. Two\u00a0complementary approaches \u2013 biological\u00a0specimen testing and drug product testing \u2013 provide critical intelligence about substances circulating in your\u00a0jurisdiction.<\/span>\u00a0<\/span><\/p>\n Testing of Nonfatal Overdoses (Bio surveillance)\u00a0<\/strong><\/p>\n Note: Focus testing at the public health level, not clinical level, as results often\u00a0don\u2019t\u00a0inform immediate treatment<\/span><\/i>\u00a0<\/span><\/p>\n Want to know more about\u00a0Biosurveillance?\u00a0<\/strong><\/p>\n Email:\u00a0<\/span>od_lab_surveillance@cdc.gov<\/span><\/a>\u00a0<\/span><\/p>\n Testing of Drug Products and Paraphernalia\u00a0<\/strong><\/p>\n Drug product testing\u00a0helps capture\u00a0supply changes\u00a0through analyzing substances\u00a0submitted\u00a0by people who use drugs within specific communities.<\/span>\u00a0<\/span><\/p>\n Want to know more about\u00a0OD2A drug\u00a0product\u00a0and paraphernalia testing?\u00a0<\/strong><\/p>\n Email:\u00a0<\/span>od2altest@cdc.gov<\/span><\/a>\u00a0<\/span>\u00a0<\/span><\/p>\n <\/span><\/p>\n Postmortem Testing\u00a0<\/strong><\/p>\n Note: Postmortem testing should not be the primary method for initially detecting emerging threats.<\/span><\/i>\u00a0<\/span><\/p>\n <\/span><\/p>\n Analyzing and Monitoring Data\u00a0<\/strong><\/p>\n Legal Considerations\u00a0<\/strong><\/p>\n Be aware of consent requirements, privacy protections, chain of custody protocols, and state\/local regulations.\u00a0Consult your health department\u2019s legal counsel for\u00a0specific guidance.<\/span>\u00a0<\/span><\/p>\n Want to know more about OD2A drug product and paraphernalia testing?<\/span><\/b>\u00a0<\/span><\/p>\n Email:\u00a0<\/span>ODSurveillance@cdc.gov<\/span><\/a>\u00a0<\/span>\u00a0<\/span><\/p>\n [\/et_pb_accordion_item][et_pb_accordion_item title=”4. Interview Key Partners” open_toggle_text_color=”#FFFFFF” closed_toggle_text_color=”#FFFFFF” _builder_version=”4.14.2″ _module_preset=”default” border_width_bottom=”0.8px” border_color_bottom=”#64748B” global_colors_info=”{}” toggle_text_color=”#FFFFFF” open=”off”]<\/p>\n Partners offer frontline insights into emerging trends. Interview:<\/p>\n [\/et_pb_accordion_item][et_pb_accordion_item title=”5. Conduct Site Visits” open_toggle_text_color=”#FFFFFF” closed_toggle_text_color=”#FFFFFF” _builder_version=”4.14.2″ _module_preset=”default” border_width_bottom=”0.8px” border_color_bottom=”#64748B” global_colors_info=”{}” toggle_text_color=”#FFFFFF” open=”off”]<\/p>\n Walkthroughs of areas experiencing high overdose rates can help clarify structural and environmental risks. During visits, assess:<\/p>\n Use this information to inform response design and identify gaps in services.<\/p>\n [\/et_pb_accordion_item][et_pb_accordion_item title=”6. Develop a List of Hypothesized Causes and Risk Factors” open_toggle_text_color=”#FFFFFF” closed_toggle_text_color=”#FFFFFF” _builder_version=”4.14.2″ _module_preset=”default” border_width_bottom=”0.8px” border_color_bottom=”#64748B” global_colors_info=”{}” toggle_text_color=”#FFFFFF” open=”off”]<\/p>\n Based on your findings, develop a list of potential causes and risk factors, such as:<\/p>\n Resource Highlight:<\/strong> The Association of Public Health Laboratories’ Model Opioids Biosurveillance Strategy<\/a> offers guidance for developing a sustainable drug biosurveillance program.<\/p>\n [\/et_pb_accordion_item][et_pb_accordion_item title=”7. Utilize Laboratory and Forensic Resources” open_toggle_text_color=”#FFFFFF” closed_toggle_text_color=”#FFFFFF” _builder_version=”4.14.2″ _module_preset=”default” border_width_bottom=”0.8px” border_color_bottom=”#64748B” global_colors_info=”{}” toggle_text_color=”#FFFFFF” open=”off”]<\/p>\n Use laboratory testing and forensic data to confirm drug composition and detect novel substances.<\/p>\n These resources help confirm what\u2019s circulating locally and how it compares to broader trends.<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.14.2″ _module_preset=”default” custom_margin=”82px|auto||auto||” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.14.2″ _module_preset=”default” global_colors_info=”{}”][dipi_dual_heading second_heading=”Continue The Toolkit” heading_tag=”h1″ heading_display=”column” fh_padding=”0px|20px|20px|20px|false|true” sh_style=”background” sh_background_style=”normal” sh_padding=”0px|20px|20px|20px|false|true” sh_margin=”-30px|0px|0px|20px|false|false” fh_padding_tablet=”0px|20px|20px|20px|false|true” fh_padding_phone=”0px|20px|20px|20px|false|true” fh_padding_last_edited=”on|desktop” fh_margin_last_edited=”off|desktop” sh_padding_tablet=”0px|20px|20px|20px|false|true” sh_padding_phone=”0px|20px|20px|20px|false|true” sh_padding_last_edited=”on|desktop” sh_margin_tablet=”-30px|0px|0px|20px|false|false” sh_margin_phone=”-20px|0px|0px|0px|false|false” sh_margin_last_edited=”on|phone” _builder_version=”4.16″ _module_preset=”default” first_heading_font=”Poppins||||||||” first_heading_text_color=”#919eb0″ first_heading_font_size=”80px” first_heading_letter_spacing=”-9px” first_heading_line_height=”1.1em” second_heading_font=”Poppins||||||||” second_heading_text_align=”left” second_heading_text_color=”#071018″ second_heading_font_size=”49px” second_heading_letter_spacing=”-5px” second_heading_line_height=”1em” custom_margin=”-1px||-38px||false|false” custom_padding=”25px|||||” first_heading_font_size_tablet=”100px” first_heading_font_size_phone=”60px” first_heading_font_size_last_edited=”on|tablet” first_heading_letter_spacing_tablet=”-7px” first_heading_letter_spacing_phone=”-4px” first_heading_letter_spacing_last_edited=”on|tablet” second_heading_font_size_tablet=”100px” second_heading_font_size_phone=”60px” second_heading_font_size_last_edited=”on|tablet” second_heading_letter_spacing_tablet=”-7px” second_heading_letter_spacing_phone=”-4px” second_heading_letter_spacing_last_edited=”on|tablet” locked=”off” global_colors_info=”{}” overlay_bg_color_gradient_type_tablet=”linear” overlay_bg_color_gradient_type_phone=”linear” overlay_bg_color_gradient_type__hover=”linear” image_bg_color_gradient_type__hover=”linear” first_heading_color_gradient_stops=”#2b87da 0%|#29c4a9 100%” second_heading_color_gradient_stops=”#2b87da 0%|#29c4a9 100%” background_text_color_gradient_stops=”#2b87da 0%|#29c4a9 100%” fh_reveal_effect_color_gradient_stops=”#2b87da 0%|#29c4a9 100%” sh_reveal_effect_color_gradient_stops=”#2b87da 0%|#29c4a9 100%” content_bg_color_gradient_type=”linear” content_hover_bg_color_gradient_type=”linear” item_bg_color_gradient_type=”linear” overlay_bg_color_gradient_type=”linear” image_bg_color_gradient_type=”linear” front_side_bg_color_gradient_type=”linear” back_side_bg_color_gradient_type=”linear”][\/dipi_dual_heading][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,1_4,1_4,1_4″ _builder_version=”4.14.2″ _module_preset=”default” custom_margin=”-4px|auto||auto||” custom_padding=”0px|||||” global_colors_info=”{}”][et_pb_column type=”1_4″ _builder_version=”4.14.2″ _module_preset=”default” global_colors_info=”{}”][et_pb_blurb url=”https:\/\/odalerts.cste.org\/?page_id=25847565″ _builder_version=”4.14.2″ _module_preset=”default” body_font=”Poppins||||||||” body_text_color=”#071018″ body_font_size=”18px” custom_margin=”|-69px||||” link_option_url=”https:\/\/odalerts.cste.org\/?page_id=25847565″ global_colors_info=”{}”]<\/p>\n < Previous:<\/strong> Describe The Event<\/p>\n [\/et_pb_blurb][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.14.2″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.14.2″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.14.2″ _module_preset=”default” global_colors_info=”{}”][et_pb_blurb url=”https:\/\/odalerts.cste.org\/?page_id=25847543″ _builder_version=”4.14.2″ _module_preset=”default” body_font=”Poppins||||||||” body_text_color=”#071018″ body_font_size=”18px” custom_margin=”|||-192px||” link_option_url=”https:\/\/odalerts.cste.org\/?page_id=25847543″ global_colors_info=”{}”]<\/p>\n Next:<\/strong> Investigate Possible Explanations<\/span> ><\/p>\n [\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,1_4,1_4,1_4″ use_custom_gutter=”on” gutter_width=”2″ custom_padding_last_edited=”on|phone” _builder_version=”4.14.2″ _module_preset=”default” background_color=”#0E151D” width_tablet=”” width_phone=”90%” width_last_edited=”on|phone” custom_margin=”|auto|29px|auto||” custom_padding=”30px|30px|30px|30px|true|true” custom_padding_tablet=”30px|30px|30px|30px|true|true” custom_padding_phone=”20px|20px|20px|20px|true|true” border_radii=”on|10px|10px|10px|10px” global_colors_info=”{}”][et_pb_column type=”1_4″ _builder_version=”4.14.2″ _module_preset=”default” background_color=”RGBA(255,255,255,0)” custom_padding=”50px|30px|50px|30px|true|true” custom_padding_tablet=”50px|30px|50px|30px|true|true” custom_padding_phone=”20px|20px|20px|20px|true|true” custom_padding_last_edited=”on|phone” link_option_url=”https:\/\/odalerts.cste.org\/?page_id=25847406″ border_radii=”on|10px|10px|10px|10px” border_width_all=”1px” border_color_all=”rgba(100,116,139,0.2)” global_colors_info=”{}” 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custom_padding_phone=”20px|20px|20px|20px|true|true” custom_padding_last_edited=”on|phone” link_option_url=”#” border_radii=”on|10px|10px|10px|10px” border_width_all=”1px” border_color_all=”rgba(100,116,139,0.2)” global_colors_info=”{}” border_color_all__hover=”rgba(100,116,139,0.5)” border_color_all__hover_enabled=”on|hover”][et_pb_blurb title=”Respond” use_icon=”on” font_icon=”||fa||900″ icon_color=”#071018″ icon_placement=”left” image_icon_width=”30px” _builder_version=”4.14.2″ _module_preset=”default” header_font=”Poppins|||on|||||” header_text_color=”#071018″ header_font_size=”16px” header_letter_spacing=”1px” body_font=”Poppins||||||||” body_text_color=”#64748B” body_font_size=”16px” body_line_height=”1.6em” image_icon_custom_margin=”||100px||false|false” max_width=”290px” custom_margin=”auto||-108px||false|false” custom_padding=”||||false|false” link_option_url=”https:\/\/odalerts.cste.org\/?page_id=25847664″ locked=”off” global_colors_info=”{}”][\/et_pb_blurb][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.24.2″ _module_preset=”default” background_enable_color=”off” custom_padding=”50px|30px|50px|30px|true|true” custom_padding_tablet=”50px|30px|50px|30px|true|true” custom_padding_phone=”20px|20px|20px|20px|true|true” custom_padding_last_edited=”on|phone” link_option_url=”#” border_radii=”on|10px|10px|10px|10px” border_width_all=”1px” border_color_all=”rgba(100,116,139,0.2)” global_colors_info=”{}” border_color_all__hover=”rgba(100,116,139,0.5)” border_color_all__hover_enabled=”on|hover”][et_pb_blurb title=”Evaluate” use_icon=”on” font_icon=”||fa||900″ icon_color=”#7ED3FC” icon_placement=”left” image_icon_width=”30px” _builder_version=”4.14.2″ _module_preset=”default” header_font=”Poppins|||on|||||” header_text_color=”#FFFFFF” header_font_size=”16px” header_letter_spacing=”1px” body_font=”Poppins||||||||” body_text_color=”#64748B” body_font_size=”16px” body_line_height=”1.6em” image_icon_custom_margin=”||100px||false|false” max_width=”290px” custom_margin=”auto||-108px||false|false” custom_padding=”||||false|false” link_option_url=”https:\/\/odalerts.cste.org\/?page_id=25847607″ locked=”off” global_colors_info=”{}”][\/et_pb_blurb][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.14.2″ _module_preset=”default” background_color=”RGBA(255,255,255,0)” custom_padding=”50px|30px|50px|30px|true|true” custom_padding_tablet=”50px|30px|50px|30px|true|true” custom_padding_phone=”20px|20px|20px|20px|true|true” custom_padding_last_edited=”on|phone” link_option_url=”#” border_radii=”on|10px|10px|10px|10px” border_width_all=”1px” border_color_all=”rgba(100,116,139,0.2)” global_colors_info=”{}” border_color_all__hover=”rgba(100,116,139,0.5)” border_color_all__hover_enabled=”on|hover”][et_pb_blurb title=”Resources” use_icon=”on” font_icon=”||divi||400″ icon_color=”#7ED3FC” icon_placement=”left” image_icon_width=”30px” _builder_version=”4.14.2″ _module_preset=”default” header_font=”Poppins|||on|||||” header_text_color=”#FFFFFF” header_font_size=”16px” header_letter_spacing=”1px” body_font=”Poppins||||||||” body_text_color=”#64748B” body_font_size=”16px” body_line_height=”1.6em” image_icon_custom_margin=”||100px||false|false” max_width=”290px” custom_margin=”auto||-108px||false|false” custom_padding=”||1px||false|false” link_option_url=”https:\/\/odalerts.cste.org\/?page_id=25847677″ locked=”off” global_colors_info=”{}”][\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"\n
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